Saturday, October 22, 2011

Ergotamine Tartrate

Ergotamine Tartrate occurs as colorless crystals, or a white to pale yellowish white or grayish white, crystalline powder. Ergotamine is an ergopeptine and part of the ergot family of alkaloids; it is structurally and biochemically closely related to ergoline. It possesses structural similarity to several neurotransmitters, and has biological activity as a vasoconstrictor.

Ergotamine is contraindicated in peripheral vascular disease (thromboangiitis obliterans, luetic arteritis, severe arteriosclerosis, thrombophlebitis, Raynaud's disease), coronary heart disease, hypertension, impaired hepatic or renal function, severe pruritus, and sepsis.

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