Common enzymes used for clinical diagnosis include acid phosphatase, alanine aminotransferase , alkaline phosphatase, amylase, angiotensin converting enzyme,gamma glutamyltransferase, lactate dehydrogenase, renin.Factors that diagnostic enzyme must have Specificity,Kinetic property (suitable Km and kcat values), Cost and Enzyme stability.Alkaline phosphatase and peroxidase are the two enzymes having biggest market, each having 20 million $,Most of diagnostic enzymes are produced by Roche or Genzyme, Widely used for EIA (enzyme immunoassay systems).
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