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Tuesday, March 20, 2012

Myristicin



  • Myristicin, or methoxysafrole, is a benzodioxole with slight MAO-inhibiting properties. Myristicin is a colorless oil that generally does not crystallize, even at extremely low temperatures (i.e., -30°C). Myristicin is mostly stable upon storage, but still subject to gradual changes in composition. 
  • Myristicin is a clear, mobile, colourless oil that does not normally freeze even at very low temperaturers, although a recent report describes its purification by repeated crystallization at -30 deg c. 
  • Myristicin, the main component of nutmeg, has been implicated to have the following adverse effects: detachment from reality, tachycardia, flushing, hypotension, drowsiness, confabulation, gagging, vomiting, ileus, paresthesias, numbness, blurred vision, hypothermia, and sweating. 
  • Myristicin has usually been isolated from natural oils by fractional distillation, as it is crystallized only with difficulty even at very low temperature. 

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